Infrastructure

X-Ray Crystallography

The primary goal of structural biology is a mechanistic understanding of biological macromolecules and of biological processes so that they can be described in the language of physics and chemistry. This requires an exact knowledge of the three-dimensional structures, of the respective molecules and of their complexes such that the spatial position of each atom can be precisely described.

Electron Microscopy

The visualization of a gene product, in particular the localization within a biological specimen is one of the basic topics in cell biology. Applying fluorescence labeling methods molecules can be detected by light microscopy, even in living cells. Nevertheless, the associated morphological structure can be identified in most cases only by electron microscopy.

Light Microscopy

The light microscopy facility offers access to state-of-the-art microscopes, including confocal microscopy, and a variety of methods to retrieve the visible information from living specimens of animals, plants or single cells. Computer tools for image analysis and visualization of data are provided.

Genome Center

The genome center is equipped with both Sanger and next generation sequencing facilities. The genome center offers small-scale sequencing services such as verifying plasmid constructs. We also offer high-throughput sequencing services, such as shotgun sequencing of genomes and metagenomes.

Mass Spectrometry

The mass spectrometry facility provides equipment, software packages and methods for targeted/untargeted metabolomics, top-down proteomics and mass spectrometry imaging using Bruker mass spectrometers (Impact-II and ScimaX). The facility aims to develop new analytical methods and support users with experimental design, data acquisition as well as data processing.

NMR Spectroscopy